产品编号:G575

产品描述:Anti-Human GPR15

反应种属:mouse, human, rat

实验方法:WB

标记:

规格:0.1mg

供应商:leinco

价格(RMB):5370.00

订购:

说明书:

Rabbit Anti-Human G Protein-Coupled Receptor 15 (GPR15)
Purified No Carrier Protein
(BOB)
Polyclonal Antibody
Prod. No.: G575
Host:      Rabbit
Conc.:     0.5 mg/ml
Pkg. Size: 1 mg, 0.1 mg, 0.5 mg
Storage: 2-8°C

Description
Specificity:
Rabbit Anti-Human G Protein-Coupled Receptor 15 (GPR15) recognizes an epitope near the N-terminus of Human, Mouse and Rat GPR15. This polyclonal antibody was purified using affinity chromatography.

Background:
Human immunodeficiency virus (HIV) and related viruses require coreceptors to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. The genes encoding human and monkey GPR15/BOB (for G protein-coupled receptor 15 and brother of Bonzo, respectively,) were recently cloned. This novel G protein-coupled receptor serves as corecptor for simian immunodeficiency virus (SIV), and for strains of HIV-2 and M-tropic HIV-1. The ligand for GPR15 has not been identified yet.

Known Species Cross Reactivity: Ms+, Hu+, Rt+
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Stability
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
WB
Western Blotting: This antibody can be used to detect Human GPR15 by Western blot analysis at a dilution of 1:500-1:2000 when used in conjunction with compatible secondary reagents, such as Goat Anti-Rabbit IgG (H&L)-Horseradish Peroxidase (Leinco Prod. No.: R1190), under either reducing or non-reducing conditions. The positive controls for Western blotting are Jurkat Whole Cell Lysate (Leinco Prod. No.: J103) and A549 Whole Cell Lysate (Human Lung Carcinoma) (Leinco Prod. No.: A181).

References
1. Heiber, M. et al. (1996) Genomics 32:462
2. Deng, H. K. et al. (1997) Nature 388:296
3. Farzan, M. et al. (1997) J. Exp. Med. 186:405
Related Products
Goat Anti-Rabbit IgG (H&L)-Horseradish Peroxidase (Leinco Prod. No.: R1190)
Jurkat Whole Cell Lysate (Leinco Prod. No.: J103)
A549 Whole Cell Lysate (Human Lung Carcinoma) (Leinco Prod. No.: A181)
G Protein-Coupled Receptor 15 (NT) Blocking Peptide (Leinco Prod. No.: G581)
Antigen Affinity Purified Polyclonal Antibodies To Growth Factors & Cytokines

Products are for research use only. Not for use in diagnostic or therapeutic procedures