产品编号:B361
产品描述:Anti-Human Bonzo(NT-2)
反应种属:human
实验方法:IHC, WB
标记:
规格:0.1mg
供应商:leinco
价格(RMB):5370.00
订购:
说明书:
Rabbit Anti-Human Bonzo
Purified No Carrier Protein
(STRL33, TYMSTR)
Polyclonal Antibody
Prod. No.: B361
Host: Rabbit
Conc.: 0.5 mg/ml
Pkg. Size: 1 mg, 0.1 mg, 0.5 mg
Storage: 2-8°C
Description
Specificity:
Rabbit Anti-Human Bonzo recognizes an epitope near the N-terminus of Human Bonzo. This polyclonal antibody was purified using affinity chromatography.
Background:
Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor (1-4). Bonzo/STRL33 serves as coreceptor for SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.
Known Species Cross Reactivity: Hu+
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Stability
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
IHC (NBF/Par.), WB
Western Blotting: This antibody can be used to detect Human Bonzo by Western blot analysis at a dilution of 1:500 when used in conjunction with compatible secondary reagents, such as Goat Anti-Rabbit IgG (H&L)-Horseradish Peroxidase (Leinco Prod. No.: R1190), under either reducing or non-reducing conditions. The positive control for Western blotting is Human Spleen Tissue Lysate (Leinco Prod. No.: H1410).
References
1. Deng, H. K. et al. (1997) Nature 388:296
2. Liao, F. et al. (1997) J. Exp. Med. 185:2015
3. Alkhatib, G. et al. (1997) Nature 388:238
4. Loetscher, M. et al. (1997) Curr. Biol. 7:652
Related Products
Goat Anti-Rabbit IgG (H&L)-Horseradish Peroxidase (Leinco Prod. No.: R1190)
Human Spleen Tissue Lysate (Leinco Prod. No.: H1410)
Bonzo (CT) Blocking Peptide (Leinco Prod. No.: B372)
Bonzo (NT-2) Blocking Peptide (Leinco Prod. No.: B373)
Anti-Human Bonzo (CT) (Leinco Prod. No.: B360)
Antigen Affinity Purified Polyclonal Antibodies To Growth Factors & Cytokines
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
