产品编号:H1463
产品描述:Anti-Hemagglutinin
反应种属:Virus
实验方法:ELISA
标记:
规格:0.1mg
供应商:leinco
价格(RMB):5370.00
订购:
说明书:
Rabbit Anti-Avian Influenza Hemagglutinin
Purified No Carrier Protein
Polyclonal Antibody
Prod. No.: H1463
Host: Rabbit
Conc.: 0.5 mg/ml
Pkg. Size: 1 mg, 0.1 mg, 0.5 mg
Storage: 2-8°C
Description
Specificity:
Rabbit Anti-Avian Influenza Hemagglutinin recognizes Avian Influenza Hemagglutinin. This polyclonal antibody was purified using affinity chromatography.
Background:
Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA.1 Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found.2 These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong.3 There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low.4 HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability.
Known Species Cross Reactivity: Virus
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Stability
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
Indirect ELISA
References
1. Thompson, W. W. et al. (2003) JAMA 289:179
2. Alexander, D. J. (2000) Vet. Microbiol. 74:3
3. Shortridge, K. F. et al. (1998) Virol. 252:331
4. Buxton Bridges, C. et al. (2000) J. Inf. Dis. 181:344
Related Products
Anti-Avian Influenza Hemagglutinin (NT) (Leinco Prod. No.: H1464)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
