产品编号:B378

产品描述:Anti-Human Beta-Defensin-2(BD-2)

反应种属:human

实验方法:ELISA, WB

标记:

规格:50ug

供应商:leinco

价格(RMB):5700.00

订购:

说明书:

Goat Anti-Human Beta-Defensin-2 (BD-2)
Biotin
(Skin-antimicrobial peptide 1 [SAP1])
Polyclonal Antibody

Prod. No.: B378
Host:         Goat
Pkg. Size: 1 mg, 50 µg

Description
Specificity:
Goat Anti-Human Beta-Defensin-2 (BD-2) recognizes Human Beta-Defensin-2. This antigen affinity purified polyclonal antibody was purified using immobilized antigen agarose chromotography.

Background:
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1, a propeptide region. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.

Human, rabbit and guinea-pig beta-defensins, as well as human beta-defensin-2 (hBD2), induce the activation and degranulation of mast cells, resulting in the release of histamine and prostaglandin D2.

Immunogen
Purified Recombinant Human BD-2 (>98%)
Formulation
This biotinylated antigen affinity purified polyclonal antibody is aseptically filtered and lyophilized from PBS with no carrier proteins or preservatives added.
Storage and Stability
This lyophilized biotinylated polyclonal antibody should be stored desiccated at -20°C. The reconstituted conjugate is stable for at least one month when stored at 2 - 8°C. For long term storage aseptically aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid More Than One Freeze Thaw Cycle.
Reported Applications
WB

Related Products
Human BD-2 ELISA Development Kit (Leinco Prod. No.: B428)
Recombinant Human Beta-Defensin-2 (Leinco Prod. No.: B113)
Anti-Human Beta-Defensin-2 (Antigen Aff. Pur.) (Leinco Prod. No.: B377)

Products are for research use only. Not for use in diagnostic or therapeutic procedures.