产品编号:I-236
产品描述:Anti-Mouse CXCL10
反应种属:mouse
实验方法:ELISA, IHC-F, N, WB
标记:
规格:100ug
供应商:leinco
价格(RMB):5595.00
订购:
说明书:
Goat Anti-Mouse Chemokine (C-X-C Motif) Ligand 10 (CXCL10)
Antigen Affinity Purified
(C7, IFI10, INP10, IP-10, SCYB10, Crg-2, GIP-10, Mob-1)
Polyclonal Antibody
Prod. No.: I-236
Host: Goat
Pkg. Size: 1 mg, 100 µg
Storage: -20°C to -70°C
Description
Specificity:
Goat Anti-Mouse Chemokine (C-X-C Motif) Ligand 10 (CXCL10) recognizes Mouse CXCL10. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
Background:
Chemokine (C-X-C motif) ligand 10 (CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family. CXCL10 is secreted by several cell types in response to IFN-γ. These cell types include monocytes, endothelial cells and fibroblasts.1 CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis.2,3 CXCL10 plays a role in the regulation of tubular cell proliferation following renal ischemia-reperfusion injury.4
Known Species Cross Reactivity: Ms+
Immunogen
Purified Recombinant Mouse IP-10 (>98%)
Formulation
This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Reconstitution
We suggest aseptically reconstituting this lyophilized, antigen affinity purified polyclonal antibody with 1 ml of sterile 1X PBS pH 7.2-7.3. This will result in a final antibody concentration of 0.1 mg/ml.
Endotoxin
<0.1 EU/µg as determined by the LAL method
Storage and Stability
The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Reported Applications
Indirect ELISA, IHC (Frozen), N, WB
References
1. Luster et al.(1985) Nature 315: 672
2. Dufour et al.(2002) J. Immunol. 168
3. Angiolillo et al.(1995) J. Exp. Med. 182: 155
4. Kaneko S. et al.(2008) Nephron Exp. Nephrol. 109: c29
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Anti-Human CXCL10-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: I-275)
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Human CXCL10 ELISA Development Kit (Leinco Prod. No.: I-423)
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
