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Anti-Mouse IL-2

产品编号:I-234

产品描述:Anti-Mouse IL-2

反应种属:mouse

实验方法:ELISA, N, WB

标记:

规格:100ug

供应商:leinco

价格(RMB):5325.00

订购:订购

说明书:

Goat Anti-Mouse Interleukin 2 (IL-2)
Antigen Affinity Purified
(TCGF, Lymphokine, T-Cell Growth Factor, Aldesleukin)
Polyclonal Antibody

Prod. No.: I-234
Host:          Goat
Pkg. Size: 1 mg, 100 µg
Storage:       -20°C to -70°C

Description
Specificity:
Goat Anti-Mouse Interleukin-2 (IL-2) recognizes Mouse IL-2. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.

Background:
Interleukin-2 (IL-2) is a potent T-cell mitogenic cytokine1 that functions as a primary regulator of T cell homeostasis and has been considered a prime candidate immunotherapeutics, both for increasing T cell levels/function and for augmenting vaccine-elicited viral-specific T cell responses.2 IL-2 plays a key role in setting the balance between immunity and tolerance. This cytokine has a dual role as the regulator of the two main phases of the immune response (proliferative and suppressive).3 IL-2 also stimulates growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes.

Known Species Cross Reactivity: Ms+
Immunogen
Purified Recombinant Mouse IL-2 (>98%)
Formulation
This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Reconstitution
We suggest aseptically reconstituting this lyophilized, antigen affinity purified polyclonal antibody with 1 ml of sterile 1X PBS pH 7.2-7.3. This will result in a final antibody concentration of 0.1 mg/ml.
Endotoxin
<0.01 EU/µg as determined by the LAL method
Storage and Stability
The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Reported Applications
Indirect ELISA, N, WB

References
1. Schachter J et al. (2009) Cytotherapy 11: 206
2. Sodora DL et al. (2009) Curr HIV Res. 7: 83
3. Alcocer-Varela J et al. (2009) Autoimmun Rev.

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Products are for research use only. Not for use in diagnostic or therapeutic procedures.