产品编号:S484
产品描述:Anti-Mouse Smac(CT)
反应种属:mouse, human, rat
实验方法:IHC, WB
标记:
规格:0.1mg
供应商:leinco
价格(RMB):5370.00
订购:
说明书:
Rabbit Anti-Mouse Second Mitochondria Derived Activator of Caspase (SMAC)
Purified No Carrier Protein
(DIABLO)
Polyclonal Antibody
Prod. No.: S484
Host: Rabbit
Conc.: 0.5 mg/ml
Pkg. Size: 1 mg, 0.1 mg, 0.5 mg
Storage: 2-8°C
Description
Specificity:
Rabbit Anti-Mouse Second Mitochondria Derived Activator of Caspase (SMAC) recognizes Mouse SMAC. This polyclonal antibody was purified using affinity chromatography.
Background:
Second Mitochondria Derived Activator of Caspase (SMAC) is a mitochondrial apoptogenic protein that is released to the cytosol in response to diverse apoptotic stimuli, including commonly used chemotherapeutic drugs.1 SMAC promotes cytochrome-c dependent activation by eliminating the inhibition of IAP - a protein that negatively regulates apoptosis or programmed cell death.2
Known Species Cross Reactivity: Ms+, Hu+, Rt+
Immunogen
Smac/DIABLO (CT) (Mouse) Blocking Peptide (Leinco Prod. No.: S504)
Blocking Peptide
Smac/DIABLO (CT) (Mouse) Blocking Peptide (Leinco Prod. No.: S504)
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Stability
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
IHC (NBF/Par.), WB
References
1. Melendez-Zajgla J. et al. (2008) J Exp Clin Cancer Res. 26: 27
2. Vucicet al. (2002) J Biol chem. 277: 12275
Related Products
Smac/DIABLO (CT) (Mouse) Blocking Peptide (Leinco Prod. No.: S504)
Anti-Human SMAC (CT) (Leinco Prod. No.: S483)
Recombinant Human SMAC (Leinco Prod. No.: S574)
Anti-Human SMAC (Antigen Aff. Pur.) (Leinco Prod. No.: S585)
Anti-Human SMAC-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: S592)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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