产品编号:S556
产品描述:Anti-Mouse SIGIRR(CT)
反应种属:mouse, human
实验方法:IHC-F, WB
标记:
规格:0.1mg
供应商:leinco
价格(RMB):5370.00
订购:
说明书:
Rabbit Anti-Mouse Single Immunoglobulin Domain-Containing IL-1 Receptor-Related Protein (SIGIRR)
Purified No Carrier Protein
(Single Ig IL-1R-Related Molecule, MGC110992, TIR8)
Polyclonal Antibody
Prod. No.: S556
Host: Rabbit
Conc.: 0.5 mg/ml
Pkg. Size: 1.0 mg, 0.1 mg, 0.5 mg
Storage: 2-8°C
Description
Specificity:
Rabbit Anti-Mouse Single Immunoglobulin Domain-Containing IL-1 Receptor-Related Protein (SIGIRR) recognizes Mouse SIGIRR. This polyclonal antibody was purified using affinity chromatography.
Background:
Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, also known as SIGIRR is a member of the IL-1 receptor family.1 It acts as a negative regulator of interleukin (IL)-1 and lipopolysaccharide (LPS) signaling.2 It also plays a critical role in gut homeostasis, intestinal inflammation, and colitis-associated tumorigenesis by maintaining the microbial tolerance of the colonic epithelium.3
Known Species Cross Reactivity: Ms+, Hu+
Immunogen
SIGIRR (CT) Blocking Peptide (Leinco Prod. No.: S559)
Blocking Peptide
SIGIRR (CT) Blocking Peptide (Leinco Prod. No.: S559)
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Stability
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
WB
References
1. Mantovani A.et al. (2003) Eur Cytokine Netw. 14: 211
2. Li xet al. (2005) J Biol chem. 280: 25233
3. Li X et al. (2007) Immunity 26: 461
Related Products
SIGIRR (CT) Blocking Peptide (Leinco Prod. No.: S559)
Anti-Human SIGIRR (Antigen Aff. Pur.) (Leinco Prod. No.: S580)
Anti-Human SIGIRR-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: S578)
Recombinant Human SIGIRR (Leinco Prod. No.: S575)
Recombinant Mouse SIGIRR (Leinco Prod. No.: S576)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
