产品编号:T309

产品描述:Anti-Human TWEAK

反应种属:mouse, human, rat

实验方法:IHC, WB

标记:

规格:0.1mg

供应商:leinco

价格(RMB):5700.00

订购:

说明书:

Rabbit Anti-Human TNF-Related Weak Inducer of Apoptosis (TWEAK)
Purified No Carrier Protein
(TNFSF12, DR3LG, Apo3-Ligand)
Polyclonal Antibody

Prod. No.: T309
Host:          Rabbit
Conc.:       0.5 mg/ml
Pkg. Size: 1 mg, 0.1 mg, 0.5 mg
Storage:       2-8°C

Description
Specificity:
Rabbit Anti-Human TWEAK recognizes Human, Mouse and Rat TWEAK. This polyclonal antibody was purified using affinity chromatography.

Background:
TNF-related weak inducer of apoptosis (TWEAK) is a member of the TNF ligand family1 that has pleiotropic biological functions including proapoptotic, proangiogenic and proinflammatory activities.2 TWEAK induces skeletal muscle atrophy.3 TWEAK functions both as a type II transmembrane protein and as a cleaved soluble protein. TWEAK transcripts are expressed in heart, brain, skeletal muscle, pancreas, immune system, ovary, and placenta.4

Known Species Cross Reactivity: Ms+, Hu+, Rt+
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Stability
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
IHC (NBF/Par.), WB

References
1. Burkly LC et al. (2005) Oncogene 24: 2613
2. Young Lee S. et al. (2003) Biochem Biophys Res Commun. 305: 789
3. Kumar A et al. (2007) FASEB J. 21: 1857
4. Aaron J. W. Hsueh et al. (2006) Molecular Endo. 20: 2528
Related Products
Anti-Human TWEAK-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: T197)
Recombinant Human TWEAK (Leinco Prod. No.: T169)
Human TWEAK ELISA Development Kit (Leinco Prod. No.: T514)
Recombinant Mouse TWEAK (Leinco Prod. No.: T524)
Anti-Human TWEAK (Antigen Aff. Pur .) (Leinco Prod. No.: T191)

Products are for research use only. Not for use in diagnostic or therapeutic procedures.