产品编号:T307
产品描述:Anti-Human TL1-A
反应种属:mouse, human
实验方法:WB
标记:
规格:0.1mg
供应商:leinco
价格(RMB):5700.00
订购:
说明书:
Rabbit Anti-Human TNF-Ligand-Related Molecule 1-A (TL1-A)
Purified No Carrier Protein
(TNFSF15, MGC129934, MGC129935, TL1, VEGI, VEGI192A)
Polyclonal Antibody
Prod. No.: T307
Host: Rabbit
Conc.: 0.5 mg/ml
Pkg. Size: 1 mg, 0.1 mg, 0.5 mg
Storage: 2-8°C
Description
Specificity:
Rabbit Anti-Human TNF-Ligand-Related Molecule 1-A (TL1-A) recognizes Human TL1-A. This polyclonal antibody was purified using affinity chromatography.
Background:
TNF-ligand-related molecule 1A (TL1A), is an endothelium-derived T cell costimulator and a ligand for tumor necrosis factor receptor superfamily members DR3 and decoy receptor 3.1 TL1A binds to the death-domain receptor (DR)3 and provides costimulatory signals to activated lymphocytes. Through this interaction, TL1A induces secretion of IFN-γ. Blockade of the TL1A/DR3 pathway may offer therapeutic opportunities in Crohn's disease.2
Known Species Cross Reactivity: Ms+, Hu+
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Stability
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
WB
References
1. Wei P et al. (2003) J Biol Chem. 278: 39251
2. Fabio Cominelli et al. (2006) PNAS 103: 8441
Related Products
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Anti-Human TL1-A (NT) (Leinco Prod. No.: T306)
TL1-A (NT) Blocking Peptide (Leinco Prod. No.: T328)
Anti-Human TL-1A-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: T234)
Human TL-1A ELISA Development Kit (Leinco Prod. No.: T516)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
