产品编号:B478
产品描述:Anti-Human BAP29
反应种属:mouse, human, rat
实验方法:IHC, WB
标记:
规格:0.1mg
供应商:leinco
价格(RMB):5700.00
订购:
说明书:
Rabbit Anti-Human B Cell Receptor-Associated Protein 29 (BAP29)
Purified No Carrier Protein
(BCR Associated Protein 29)
Polyclonal Antibody
Prod. No.: B478
Host: Rabbit
Conc.: 0.5 mg/ml
Pkg. Size: 1 mg, 0.1 mg, 0.5 mg
Storage: 2-8°C
Description
Specificity:
Rabbit Anti-Human B Cell Receptor-Associated Protein 29 (BAP29) recognizes an epitope in the intemediate domain of Human, Mouse and Rat BAP29. This polyclonal antibody was purified using affinity chromatography.
Background:
Bap29 and the related protein Bap31 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family.1,2 These two proteins are highly homologous and can form homo- and heterodimers. Both Bap29 and Bap31 interact with membrane-bound immunoglobulins (mIgs), such as IgM and IgD, which with Ig-α/Ig-β heterodimers form B cell antigen receptors. Binding of the Bap29/Bap31 heterodimer correlates with the ER retention of non-Ig-α/Ig-β bound mIg complexes, suggesting that Bap29 and Bap31 may act as chaperones transmembrane regions of various proteins. Bap29 possesses multiple isoforms.
Known Species Cross Reactivity: Ms+, Hu+, Rt+
Immunogen
B Cell Receptor-Associated Protein 29 (Intermediate Domain) Blocking Peptide (Leinco Prod. No.: B498)
Blocking Peptide
B Cell Receptor-Associated Protein 29 (Intermediate Domain) Blocking Peptide (Leinco Prod. No.: B498)
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Stability
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
IHC (NBF/Par.), WB
Western Blotting: This antibody can be used to detect Human, Mouse and Rat BAP29 by Western blot analysis at a concentration of 0.5 to 1 µg/ml when used in conjunction with compatible secondary reagents, such as Goat Anti-Rabbit IgG (H&L)-Horseradish Peroxidase (Leinco Prod. No.: R1190), under either reducing or non-reducing conditions. The positive control for Western blotting is Human Heart Tissue Lysate (Leinco Prod. No.: H1405).
References
1. Ng, F. et al. (1997) J. Cell Biol. 139:327
2. Schamel, W. W. et al. (2003) Proc. Natl. Acad. Sci. USA 100:9861
Related Products
B Cell Receptor-Associated Protein 29 (Intermediate Domain) Blocking Peptide (Leinco Prod. No.: B498)
Goat Anti-Rabbit IgG (H&L)-Horseradish Peroxidase (Leinco Prod. No.: R1190)
Human Heart Tissue Lysate (Leinco Prod. No.: H1405)
Anti-Human B Cell Receptor-Associated Protein 29 (CT) (BAP29) (Leinco Prod. No.: B477)
B Cell Receptor-Associated Protein 29 (CT) Blocking Peptide (Leinco Prod. No.: B497)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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