产品编号:H101
产品描述:Anti-Human FSH-β
反应种属:human
实验方法:ELISA
标记:
规格:1.0 ml
供应商:leinco
价格(RMB):2670.00
订购:
说明书:
Anti-Human Follicle Stimulating Hormone Beta (FSH-β )
Horseradish Peroxidase (HRPO)
Monoclonal Antibody
Prod. No.: H101
Clone: 181
Isotype: Mouse IgG
Conc.: 0.5 mg/ml
Pkg. Size: 1.0 ml
Description
Specificity:
Mouse Anti-Human Follicle Stimulating Hormone β (Clone 181) recognizes Human Follicle Stimulating Hormone β. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
Follicle-stimulating hormone (FSH) is a heterodimeric glycoprotein and is composed of alpha and beta subunits. Alpha subunit is common to FSH and LH, while a unique beta subunit determines the biological specificity of each hormone. The synthesis of beta subunit is the primary rate-limiting step in the synthesis of each hormone.1 Human mutations in the FSH beta gene have been shown to produce complete deficiency states in which pubertal development and reproductive capacity are inhibited.2
Reporter Molecule:
Horseradish Peroxidase (HRPO) is an enzyme purified from horseradish root with a molecular weight of approximately 44 kDa.
Affinity:
9.0 X 10 9
Host Species
Mouse
Immunogen
Purified Recombinant Human Follicle Stimulating Hormone Beta (>98%)
Formulation
This horseradish peroxidase conjugate is supplied in a specially formulated stabilization diluent.(Leinco Prod. No.: S509)
Cross Reactivity
Paired with Leinco Prod. No. F103, Clone No. 176: FSH 100%, BhCG <1%, LH <4%, ihCG*, TSH <1% *3,000 mlU/ml hCG causes 4.5% decrease in observed FSH. At higher concentrations of hCG, observed FSH reduced to zero. Paired with Leinco Prod. No. C102, Clone No. 151: FSH 100%, BhCG <1%, ihCG **, FSH <1%, TSH <1%.** At high concentrations of hCG, observed FSH reduced to zero.
Storage and Stability
Stable for at least one year when stored at 2°C - 8°C. Do not freeze.
Reported Applications
ELISA Det
References
1. Ryu KZ et al. (2000) J Korean Soc Endocrinol. 15: 179
2. Sluss Patrick et al. (2002) J clin endocrin and metabolism 87: 3702
Related Products
Anti-Human Follicle Stimulating Hormone Beta Purified (Leinco Prod. No.: F102)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
