产品编号:F102
产品描述:Anti-Human FSH-β Purified
反应种属:human
实验方法:ELISA
标记:
规格:1.0 mg
供应商:leinco
价格(RMB):2280.00
订购:
说明书:
Anti-Human Follicle Stimulating Hormone Beta (FSH-β)
Purified No Carrier Protein
Monoclonal Antibody
Prod. No.: F102
Clone: 181
Isotype: Mouse IgG
Conc.: 1.0 mg/ml
Pkg. Size: 1.0 mg
Storage: -20°C
Description
Specificity:
Mouse Anti-Human Follicle Stimulating Hormone Beta (FSH-β) (Clone 181) recognizes Human Follicle Stimulating Hormone Beta. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
Follicle-stimulating hormone (FSH) is a heterodimeric glycoprotein and is composed of alpha and beta subunits. Alpha subunit is common to FSH and LH, while a unique beta subunit determines the biological specificity of each hormone. The synthesis of beta subunit is the primary rate-limiting step in the synthesis of each hormone.1 Human mutations in the FSH beta gene have been shown to produce complete deficiency states in which pubertal development and reproductive capacity are inhibited.2
Affinity:
9.0 X 10 9
Host Species
Mouse
Immunogen
Purified Recombinant Human FSH-β (>98%)
Formulation
This purified antibody is supplied in 0.01 M phosphate buffered saline (PBS), pH 7.4, containing 0.09% sodium azide.
Cross Reactivity
Paired with Leinco Prod. No. F103, Clone No. 176: FSH 100%, BhCG < 1%, LH < 4%, ihCG *, TSH < 1% * 3,000 mIU/ml hCG causes 4.5% decrease in observed FSH. At higher concentrations of hCG, observed FSH reduced to zero. Paired with Leinco Prod. No. C102, Clone No.151: FSH 100%, BhCG < 1%, ihCG **, FSH < 1%, TSH < 1% **At high concentrations of hCG, observed FSH reduced to zero.
Storage and Stability
For long term storage freeze working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
References
1. Ryu KZ et al. (2000) J Korean Soc Endocrinol. 15: 179
2. Sluss Patrick et al. (2002) J clin endocrin and metabolism 87: 3702
Related Products
Anti-Human Follicle Stimulating Hormone Beta-Horseradish Peroxidase (Leinco Prod. No.: H101)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
