产品编号:I-438
产品描述:Anti-Mouse IFNγ
反应种属:mouse
实验方法:ELISA, N, IP, WB
标记:
规格:500ug
供应商:leinco
价格(RMB):4200.00
订购:
说明书:
Anti-Mouse Interferon-Gamma (IFN-γ)
Purified Low Endotoxin Functional Formulation
(Immune Interferon, Type II Interferon, T Cell Interferon, MAF, IFNG, IFG, IFI)
Monoclonal Antibody
Prod. No.: I-438
Clone: H22
Isotype: Armenian Hamster IgG
Conc.: 1.0 mg/ml
Pkg. Size: Custom, 50 µg, 500 µg
Storage: Sterile 2-8°C
Description
Specificity:
Armenian Hamster Anti-Mouse Interferon-Gamma (IFN-γ) (Clone H22) recognizes an epitope on Mouse IFN-γ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.3
Host Species
Armenian Hamster
Immunogen
Purified Recombinant Mouse IFN-γ (>98%)
Formulation
This antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Storage and Stability
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
N, IP, WB
References
1. Goeddel DV et al. (1982) Nature 298: 859
2. Wilson CB et al. (2007) Adv. Immunol. 96: 41
3. Hume DA et al. (2004) J Leukoc Biol. 75: 163
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
