产品编号:I-440
产品描述:Anti-Mouse IFNβ Purified
反应种属:mouse
实验方法:IP, WB
标记:
规格:50µg
供应商:leinco
价格(RMB):3300.00
订购:
说明书:
Anti-Mouse IFNβPurified
(Interferon Beta)
Monoclonal Antibody
Prod. No.: I-440
Clone: MIB-5E9.1
Isotype: Armenian Hamster IgG
Conc.: 0.1 mg/ml
Pkg. Size: 50 µg, 500 µg
Description
Specificity:
Armenian Hamster Anti-Mouse IFNβ (Clone MIB-5E9.1) recognizes Mouse IFNβ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
Interferons (IFN) consist of two classes. The type I IFN class consists of 20 highly similar IFN-α proteins and a single IFN-ß protein. The second class, type II IFN, consists of a single protein, IFN-γ. IFN-α and IFN-ß signal through the same cell surface receptor IFNAR1 and have a similar range of biological activities including antiviral and antiproliferative activity. The type I IFNs also influence activation, growth and differentiation of T cells, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. IFN-ß has recently proven to be beneficial in patients with multiple sclerosis and could also be a potential therapy for rheumatoid arthritis. It is unclear what cellular mechanisms are involved in IFN-ß’s therapeutic effects, but they may be caused by a restoration of balance between pro- and anti-inflammatory cytokines.
Host Species
Armenian Hamster
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Stability
This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
IP, WB
Related Products
Armenian Hamster IgG Isotype Control-Low Endotoxin Functional Formulation (Leinco Prod. No.: I-140)
Anti-Mouse Interferon Beta (IFNβ) Low Endotoxin Functional Formulation (Leinco Prod. No.: I-439)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
