产品编号:C162

产品描述:Anti-Human Cytokeratin 19 Purified

反应种属:human

实验方法:IHC, WB

标记:

规格:200ug

供应商:leinco

价格(RMB):3375.00

订购:

说明书:

Anti-Human Cytokeratin 19 Purified
(PTPN22, PTPN8 (former), PEP)
Monoclonal Antibody
Prod. No.: C162
Clone:     BA17
Isotype:   Mouse IgG1
Conc.:     0.5 mg/ml
Pkg. Size: 200ug
Storage:   2-8°C

Description
Specificity:
Anti-Human Cytokeratin 19 (clone BA17) reacts with the smallest human cytokeratin (Mr 40 kDa).1 The antibody reacts specifically with cytokeratin 19 and has no reactivity with other cytokeratins.

Antigen Distribution:
Anti-Cytokeratin 19 reacts strongly with luminal (secretory) epithelial cells but does not stain the basal (myoepithelial) cells. There is a subset of secretory epithelial cells which were Keratin 19- and are thought to be precursors to keratin 19+ cells.1,2

Background:
Cytokeratin 19, a type I intermediate filament protein, it is the smallest known acidic cytokeratin. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours.

Known Species Cross Reactivity: Hu+
Host Species
Mouse
Immunogen
Mammary organoids
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Stability
This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
IHC (NBF/Par.), WB

References
1. Bartek J. et al. (1985) J. Cell Sci. 75:17
2. Bartek J. et al. (1985) Int. J. Cancer 36:299

Products are for research use only. Not for use in diagnostic or therapeutic procedures