产品编号:T250
产品描述:Anti-Mouse TNFR1
反应种属:mouse
实验方法:N, IP
标记:
规格:500ug
供应商:leinco
价格(RMB):4200.00
订购:
说明书:
Anti-Mouse TNFR1 Purified Low Endotoxin Functional Formulation
(CD120α)
Monoclonal Antibody
Prod. No.: T250
Clone: 55R-170
Isotype: Armenian Hamster IgG
Conc.: 1.0 mg/ml
Pkg. Size: Custom, 50ug, 500ug
Description
Specificity:
Armenian Hamster Anti-Mouse CD120 (Clone 55R-170) recognizes Mouse CD120. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-α and TNF-ß (also known as LT-α). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-ĸB induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.
Host Species
Armenian Hamster
Formulation
This antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Storage and Stability
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
N, IP
Related Products
Armenian Hamster IgG Isotype Control-Low Endotoxin Functional Formulation (Leinco Prod. No.: I-140)
Anti-Mouse TNFR1 - Biotin (Leinco Prod. No.: T249)
Anti-Mouse TNFR1-Purified (Leinco Prod. No.: T248)
Products are for research use only. Not for use in diagnostic or therapeutic procedures
