产品编号:T249

产品描述:Anti-Mouse TNFR1-Biotin

反应种属:mouse

实验方法:FC, ELISA.

标记:

规格:500ug

供应商:leinco

价格(RMB):3150.00

订购:

说明书:

Anti-Mouse TNFR1(CD120α)Biotin
Monoclonal Antibody

Prod. No.: T249
Clone:     55R-170
Isotype:   Armenian Hamster IgG
Conc.:     0.1 mg/ml
Pkg. Size: 50ug, 500ug

Description
Specificity:
Armenian Hamster Anti-Mouse CD120α (Clone 55R-170) recognizes Mouse CD120α. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background:
Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-α and TNF-ß (also known as LT-α). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-ĸB induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.

Host Species
Armenian Hamster
Formulation
This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Stability
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
Reported Applications
ELISA Det, FC

Related Products
Armenian Hamster IgG Isotype Control-Biotin (Leinco Prod. No.: I-445)
Anti-Mouse TNFR1 Low Endotoxin Functional Formulation (Leinco Prod. No.: T250)
Anti-Mouse TNFR1-Purified (Leinco Prod. No.: T248)

Products are for research use only. Not for use in diagnostic or therapeutic procedures