产品编号:T258
产品描述:Anti-Mouse TNF-α
反应种属:mouse
实验方法:ELISA, N, IP, WB
标记:
规格:500ug
供应商:leinco
价格(RMB):4350.00
订购:
说明书:
Anti-Mouse Tumor Necrosis Factor-Alpha(TNF-α)Purified Low Endotoxin Functional Formulation
(Tumor Necrosis Factor Ligand Superfamily Member 2 (TNFSF2), Cachectin, Differentiation-Inducing Factor (DIF), Necrosin, Cytotoxin)
Monoclonal Antibody
Prod. No.: T258
Clone: TN3-19.12
Isotype: Armenian Hamster IgG
Conc.: 1.0 mg/ml
Pkg. Size: Custom, 50ug, 500ug
Description
Specificity:
Armenian Hamster Anti-Mouse TNFa (Clone TN3-19.12 ) recognizes Mouse TNFa. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
The tumor necrosis factor (TNF-alpha) is a multifaceted polypeptide cytokine known as a mediator of inflammation and immunity.1 It may mediate some of the significant changes in cellular homeostasis which accompany the invasion of the mammalian host by viruses, bacteria, and parasites.2 TNF-α is an acute phase protein which initiates a cascade of cytokines and increases vascular permeability, thereby recruiting macrophage and neutrophils to a site of infection. TNF-α secreted by the macrophage causes blood clotting which serves to contain the infection. TNF-α has been detected in synovial fluid of patients with rheumatoid arthritis.
Host Species
Armenian Hamster
Formulation
This antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Storage and Stability
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
ELISA Cap, N, IP, WB
References
1. El-Harith el-HA et al. (2004) Saudi Med J. 25: 135
2. Adolf GR et al. (1990) Infec Immun. 58: 3996
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Products are for research use only. Not for use in diagnostic or therapeutic procedures
