产品编号:LD-7510
产品描述:Bovine CardiacTroponin-I
反应种属:Bovine
实验方法:
标记:
规格:1 mg
供应商:Life Diagnostics
价格(RMB):15400.00
说明书:
Bovine Cardiac Troponin-I
Catalog No. 7510
Analysis SDS PAGE: ~24 kDa band.
Purity 90%
Concentration 0.585 mg/ml (Bradford assay vs. BSA)
Buffer 8 M Urea, 50 mM TrisCl (pH 7.4), 100 mM NaCl, 2 mM EDTA, 5 mM b-mercaptoethanol
(may also contain ~0.5 mM CaCl2)
Storage -20 to -70oC
Source Fresh frozen cow heart
Troponin I (TnI) is one of three subunits that form the troponin complex of the thin
filaments of striated muscle. The troponin complex serves as a calcium-sensitive switch
that regulates striated muscle contraction. Troponin I binds actin and inhibits actomyosin
ATPase activity in the absence of calcium. Cardiac troponin I is characterized by a
molecular weight of ~24 kDa. It is expressed only in the heart and has proved to be a
specific biomarker for cardiac muscle damage. Cardiac troponin-I is purified by ionexchange
chromatography in conjunction with calcium dependent affinity
chromatography on troponin-C agarose.