产品编号:LD-7310

产品描述:Dog CardiacTroponin-I

反应种属:Dog

实验方法:

标记:

规格:100 mg

供应商:Life Diagnostics

价格(RMB):5000.00

订购:

说明书:

Canine Cardiac Troponin-I
Catalog No.           7310
Analysis                SDS PAGE: ~24 kDa band.
Purity                95%
Concentration       0.25 - 2 mg/ml
Buffer                    8 M Urea, 50 mM TrisCl (pH 7.4), 100 mM NaCl, 2 mM EDTA, 5 mM -mercaptoethanol

                              (may also contain ~0.5 mM CaCl2)
Storage                  -20 to -70oC
Source                   Fresh frozen canine cardiac muscle
Troponin I (TnI) is one of three subunits that form the troponin complex of the thin
filaments of striated muscle. The troponin complex serves as a calcium-sensitive switch
that regulates striated muscle contraction. Troponin I binds actin and inhibits actomyosin
ATPase activity in the absence of calcium. Cardiac troponin I is characterized by a
molecular weight of ~24 kDa. It is expressed only in the heart and has proved to be a
specific biomarker for cardiac muscle damage. Cardiac troponin-I is purified by ionexchange
chromatography in conjunction with calcium dependent affinity
chromatography on troponin-C agarose.