产品编号:LD-7110

产品描述:Mouse CardiacTroponin-I

反应种属:Mouse

实验方法:

标记:

规格:1 mg

供应商:Life Diagnostics

价格(RMB):44000.00

订购:

说明书:

Mouse Cardiac Troponin-I
Catalog No.          7110
Analysis               SDS PAGE: ~24 kDa band.
Purity               90%
Concentration      0.25 - 2 mg/ml
Buffer                   8 M Urea, 50 mM TrisCl (pH 7.4), 100 mM NaCl, 2 mM EDTA, 5 mM b-mercaptoethanol

                            (may also contain ~0.5 mM CaCl2)
Storage                -20 to -70oC
Source                 Fresh frozen mouse heart
Troponin I (TnI) is one of three subunits that form the troponin complex of the thin
filaments of striated muscle. The troponin complex serves as a calcium-sensitive switch
that regulates striated muscle contraction. Troponin I binds actin and inhibits actomyosin
ATPase activity in the absence of calcium. Cardiac troponin I is characterized by a
molecular weight of ~24 kDa. It is expressed only in the heart and has proved to be a
specific biomarker for cardiac muscle damage. Cardiac troponin-I is purified by ionexchange
chromatography in conjunction with calcium dependent affinity
chromatography on troponin-C agarose.