产品编号:LD-1220

产品描述:Human Cardiac Troponin-I, Recombinant

反应种属:Human

实验方法:

标记:

规格:1 mg

供应商:Life Diagnostics

价格(RMB):15400.00

订购:

说明书:

Human Cardiac Troponin-I
(Recombinant)
Catalog No.                 1220
SDS PAGE                   24 kDa band
Purity                         98%
Concentration             0.5 - 4 mg/ml
Buffer                            6M urea, 50 mM Tris (pH 8.0)
Storage                        -20oC (avoid repeated freeze thawing)
Source                          Expressed in E. coli.
Troponin I (TnI) is one of three subunits that form the troponin complex of the thin
filaments of striated muscle. The troponin complex serves as a calcium-sensitive switch
that regulates striated muscle contraction. Troponin I binds actin and inhibits actomyosin
ATPase activity in the absence of calcium. Cardiac troponin I is characterized by a
molecular weight of ~24 kDa. It is expressed only in the heart and has proved to be a
specific biomarker for heart disease. Recombinant cardiac troponin-I is purified from E.
coli extracts using ion-exchange chromatography in conjunction with calcium dependent
affinity chromatography on troponin-C agarose. Recombinant human cardiac troponin-I
is recognized by antibodies targeted against native human cardiac troponin-I.