产品编号:HIV-142-500ug

产品描述:Recombinant HTLV-1 gp46 mosaic

反应种属:

实验方法:

标记:

规格:500µg

供应商:Prospec

价格(RMB):8400.00

订购:

说明书:

HTLV-1 gp46 mosaic
HTLV-I gp46 Mosaic Recombinant
Catalog No. HIV-142

Introduction:
Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).

Description:
The E.Coli derived recombinant mosaic protein contains the gp46 immunodominant regions, 162-214 amino acids and 242-257 amino acids.

Purification Method:
HTLV-1 gp46 was purified by proprietary chromatographic technique.

Purity:
HTLV-1 gp46 protein is >95% pure as determined by 10% SDS-PAGE (coomassie staining) and RP-HPLC.

Formulation:
10mM NaPO4 pH 6.0, 0.1% SDS, 1mM DTT, 1mM EDTA.

Storage:
HTLV-1 gp46 protein is shipped at ambient temperature.
Upon arrival, Store at -20°C.

Stability:
Five years frozen. One month in solution at room temperature.

Applications:
HTLV-1 gp46 can be used as an antigen in ELISA and Western Blots. Excellent reagent for correct detection of HTLV infections, with minimal specificity problems.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.