产品编号:HIV-107-1000ug

产品描述:Recombinant HTLV-1 Envelope

反应种属:

实验方法:

标记:

规格:1000µg

供应商:Prospec

价格(RMB):14000.00

订购:

说明书:

HTLV-1 Envelope
HTLV-1 Envelope Recombinant
Catalog No. HIV-107

Introduction:
Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).

Description:
The E.Coli derived recombinant protein contains the C- terminus of gp46 and most of p21E of HTLV-1. This non-fusion, E. coli-derived protein, starts from HIV-1 env. Amino acid 165, and is ending in amino acid 440, Mw 27 kDa.

Purification Method:
HTLV-1 Envelope was purified by proprietary chromatographic technique.

Purity:
HTLV-1 Envelope protein is >95% pure as determined by 10% PAGE (coomassie staining) and RP-HPLC.

Formulation:
10mM Na-PO4 pH 6.0, 0.1% SDS and 1mM DTT.

Storage:
HTLV-1 Envelope protein is shipped at ambient temperature. Upon arrival, Store at -20°C.

Stability:
Five years frozen. One month in solution at room temperature.

Specificity:
Immunoreactive with all sera of HTLV-I and HTLV-II infected individuals with antibody response to HTLV envelope.

Applications:
HTLV-1 Envelope can be used as an antigen in ELISA and Western Blots. Excellent reagent for correct detection of HTLV infections, with minimal specificity problems.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.