产品编号:PRO-736-5ug
产品描述:Recombinant Human PDCD1LG2(PDCD1LG2)
反应种属:
实验方法:
标记:
规格:5µg
供应商:Prospec
价格(RMB):3780.00
说明书:
PDCD1LG2 Human
Programmed Cell Death 1 Ligand 2 Human Recombinant
Catalog No. PRO-736
Synonyms:
CD273, B7DC, PD-L2, Btdc, PDL2, PDCD1L2, MGC142238, MGC142240, bA574F11.2, Programmed cell death 1 ligand 2, Programmed death ligand 2, PDCD1 ligand 2, PD-1 ligand 2, Butyrophilin B7-DC, B7-DC, PDCD1LG2.
Introduction:
PDCD1LG2 (B7-DC, CD273), is part of the B7 family of proteins. PDCD1LG2 plays an important regulatory role during the immune response of the host to the pathogen.
PDCD1LG2 is a marker of angioimmunoblastic T-cell lymphoma and B-cell small lymphocytic lymphoma/chronic lymphocytic leukemia. HRV-16 infection or exposure to dsRNA induces epithelial PDCD1LG2. PDCD1LG2 functions as an inhibitor to T cell activation. PDCD1LG2 negatively regulates human T cell activation and therefore acts an a candidate protein for immunotherapeutic approaches aimed to attenuate pathological immune responses.
Description:
PDCD1LG2 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain fused to a GST tag containing 274 amino acids (1-274) and having a total molecular mass of 56kDa.
PDCD1LG2 is purified by proprietary chromatographic techniques.
Source:
Escherichia Coli.
Physical Appearance:
Sterile Filtered clear solution.
Formulation:
PDCD1LG2 is supplied in 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol.
Stability:
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.
Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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