产品编号:ANT-235-200ul
产品描述:Polyclonal Rabbit Anti Myc
反应种属:
实验方法:
标记:
规格:200µl
供应商:ProSpec
价格(RMB):8120.00
说明书:
Myc Antibody
Myc, Polyclonal Antibody
Catalog No. ANT-235
Synonyms:
MYC, CMYC, C-MYS, V-MYC, P64
Type:
Polyclonal Rabbit Antibody
Introduction:
c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Clone:
PPMYCSHG
Description:
Polyclonal antibodies are produced by immunizing rabbits with synthetic peptide (EQKLISEEDL) coupled to KLH.
Formulation:
Serum with 0.02% sodium azide.
Stability / Shelf Life:
2 years at -20ºC. 1 month at 4ºC.
Dilution:
Western Blotting: 1:500.
Applications:
Western Blot, Immunoprecipitation
Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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