产品编号:ANT-235-100ul

产品描述:Polyclonal Rabbit Anti Myc

反应种属:

实验方法:

标记:

规格:100µl

供应商:ProSpec

价格(RMB):4410.00

订购:

说明书:

Myc Antibody
Myc, Polyclonal Antibody
Catalog No. ANT-235

Synonyms:
MYC, CMYC, C-MYS, V-MYC, P64

Type:
Polyclonal Rabbit Antibody

Introduction:
c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Clone:
PPMYCSHG

Description:
Polyclonal antibodies are produced by immunizing rabbits with synthetic peptide (EQKLISEEDL) coupled to KLH.

Formulation:
Serum with 0.02% sodium azide.

Stability / Shelf Life:
2 years at -20ºC. 1 month at 4ºC.

Dilution:
Western Blotting: 1:500.

Applications:
Western Blot, Immunoprecipitation

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.