产品编号:ANT-162-100ul
产品描述:Polyclonal Rabbit Anti Pancreas Duodenum Homeobox-1(PDX-1)
反应种属:
实验方法:WB,IHC
标记:
规格:100µl
供应商:ProSpec
价格(RMB):3360.00
说明书:
PDX-1 antibody
Pancreas Duodenum Homeobox-1, Polyclonal Rabbit Antibody
Catalog No. ANT-162
Synonyms:
IPF1, IUF1, IDX-1, MODY4, PDX1, STF-1, Insulin promoter factor 1, Pancreas Duodenum Homeobox-1
Type:
Polyclonal Rabbit Antibody
Introduction:
PDX1 activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. IPF1 is particularly involved in glucose-dependent regulation of insulin gene transcription. Pancreas Duodenum Homeobox-1 binds preferentially the DNA motif 5'-[ct]taat[tg]-3'. during development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. at adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.
Host:
Rabbit.
Immunogen:
Recombinant PDX1 E.Coli derived
Specificity:
Human and Mouse PDX-1
Molecular Weight:
35-40 kDa
Stability:
Stable for 2 yeas at -20°C. Avoid freeze/thaw cycles.
Application:
Western Blot: 1:1,000
Immunohistochemistry: 1:500
Optimal working dilutions must be determined by end user.
Routinely evaluated by western blot on lysates of rat pancreatic cell line INS-1.
Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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