产品编号:ANT-223-100ug

产品描述:Mouse Anti Myc

反应种属:

实验方法:WB，IP

标记:

规格:100µg

供应商:ProSpec

价格(RMB):2170.00

订购:

说明书:

Myc Antibody
Myc, Mouse Antibody
Catalog No. ANT-223

Synonyms:
MYC, CMYC, C-MYS, V-MYC, P64

Type:
Mouse Antibody Monoclonal

Introduction:
c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Clone:
PMYCSHG

Description:
Monoclonal antibodies are produced by immunizing mouse with synthetic peptide (EQKLISEEDL) coupled to KLH.

Ig Subclass:
Mouse IgG1.

Formulation:
1×PBS & 50% glycerol

Stability / Shelf Life:
2 years at -20ºC. 1 month at 4ºC.

Dilution:
Western Blotting: 0.5µg/ml

Applications:
Western Blot, Immunoprecipitation

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.