产品编号:ANT-182-200ul

产品描述:Polyclonal Anti Anthrax PA

反应种属:

实验方法:WB

标记:

规格:200µl

供应商:ProSpec

价格(RMB):8260.00

订购:

说明书:

Anthrax PA Antibody
Anthrax PA Polyclonal Antibody
Catalog No. ANT-182

Type:
Rabbit Anti Human Polyclonal Antibody

Background:
Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family(2).

Contents:
200µl PBS containing 0.2% gelatin and 0.05% sodium azide.

Isotype:
Rabbit Ig

Antigen:
Anthrax PA Antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 240-254 of the Anthrax PA protein (~83 kD). Anthrax PA Antibody is cleaved from the 83 kDa form to the 63 kDa form at amino acids 164-167. Thus the Anthrax PA antibody (made against amino acids 250-250) should recognize both the 83 kDa and 63 kDa PA forms, but not the 20 kDa cleavage fragment

Applications:
This polyclonal antibody can be used for detection of Anthrax PA protein in western blot, 1:1000

Storage:
Store at 4°C, stable for 6 months. For long-term storage, store at
-20°C.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.