产品编号:ANT-263-500ug

产品描述:Mouse Anti Human CD40

反应种属:Human

实验方法:

标记:

规格:500µg

供应商:ProSpec

价格(RMB):2170.00

订购:

说明书:

CD40 Antibody
CD40, Mouse Anti-Human
Catalog No. ANT-263

Synonyms:
p50, Bp50, CDW40, MGC9013, TNFRSF5, CD40.

Type:
Mouse Anti Human Monoclonal

Introduction:
CD40 is part of the TNF-receptor superfamily. CD40 is a necessary mediator for vast range of immune and inflammatory responses together with T cell-dependent immunoglobulin class switching, memory B cell growth, and germinal center formation. The transcription factor AKNA regulates the expression of CD40 and its ligand, which is vital for homotypic cell interactions. Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand is crucial for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is the receptor for TNFSF5/CD40L.

Clone:
hCD40

Immunogen:
Activated Human B cells

Ig Subclass:
Mouse IgG1

Purification Method:
Protein-A

Protein concentration:
1mg/ml in PBS (after reconstitution)

Storage Procedures:
Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. 

Reconstitution:
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Stability / Shelf Life:
Two years lyophilized, one month in solution at 4°C.

Antibody Properties:
Staining antibody. For staining, use 10µl/106 cells.

Available Conjugates:
This antibody is also available conjugated to biotin and FITC. For staining with biotin or FITC-conjugated antibody use 5-10µl/106 cells.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.