产品编号:ANT-276-500ug

产品描述:Mouse Anti Human CD11b FITC

反应种属:Human

实验方法:

标记:FITC

规格:500µg

供应商:ProSpec

价格(RMB):3500.00

订购:

说明书:

CD11b Antibody, FITC
CD11b, Mouse Anti-Human, FITC
Catalog No. ANT-276

Synonyms:
Integrin alpha-M, Cell surface glycoprotein MAC-1 subunit alpha, CR-3 alpha chain, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b antigen, ITGAM, CR3A, MO1A, CD11B, MAC-1, MAC1A, MGC117044.

Type:
Mouse Anti Human Monoclonal

Introduction:
Integrins are heterodimeric integral membrane proteins consisting of an α chain and a ß chain. CD11b is an I-domain including α integrin combines with the ß 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor also called MAC1. The α M beta 2 integrin is crucial in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

Clone:
hCD11b

Immunogen:
Purified human PBL Monocytes

Ig Subclass:
Mouse IgG1

Purification Method:
Ion exchange column

Protein concentration:
1mg/ml in PBS (after reconstitution)

Storage Procedures:
Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

Reconstitution:
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Stability / Shelf Life:
Two years lyophilized, one month in solution at 4°C.

Antibody Properties:
Blocking and staining antibody. For staining, use 10µl/106 cells. Titer for blocking LPS binding should be determined by the investigator.

Available Conjugates:
This antibody is also available unconjugated and conjugated to Biotin. For staining with biotin or FITC-conjugated antibody use 5-10µl/106 cells.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.