产品编号:ANT-135-500ug

产品描述:Rat Anti Mouse CD11a

反应种属:mouse

实验方法:

标记:

规格:500µg

供应商:ProSpec

价格(RMB):2170.00

订购:

说明书:

CD11a Antibody
CD11a (LFA-1), Rat Anti-Mouse
Catalog No. ANT-135

Synonyms:
Integrin, alpha L, CD11A, p180, alpha polypeptide, ITGAL, LFA-1, LFA1A

Type:
Rat Anti Mouse Monoclonal

Introduction:
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling.

Clone:
mCD11a

Immunogen:
Enriched mouse peritoneal macrophages

Ig Subclass:
Rat IgG2b

Purification Method:
Ion exchange column

Protein concentration:
1mg/ml in PBS (after reconstitution)

Storage Procedures:
Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.

Reconstitution:
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Stability / Shelf Life:
Two years lyophilized, one month in solution at 4oC.

Antibody Properties:
Staining and blocking antibody. For staining, use 10 µl/106 cells. This antibody will block signaling through the CD11a molecule. Titer for blocking should be determined by the investigator.

Usage:
Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.