产品编号:ANT-136-500ug

产品描述:Rat Anti Mouse CD11b-FITC

反应种属:mouse

实验方法:

标记:FITC

规格:500µg

供应商:ProSpec

价格(RMB):3500.00

订购:

说明书:

CD11b FITC Antibody
CD11b FITC, Rat Anti-Mouse
Catalog No. ANT-136

Synonyms:
Integrin, alpha M, CR3A, MO1A, CD11B, MAC-1, MAC1A, MGC117044, ITGAM

Type:
Rat Anti Mouse Monoclonal

Introduction:
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Integrin alpha-m/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. CD-11b is identical with cr-3, the receptor for the ic3b fragment of the third complement component. CD-11b probably recognizes the r-g-d peptide in c3b. Integrin alpha-m/beta-2 is also a receptor for fibrinogen, factor x and icam1. it recognizes p1 and p2 peptides of fibrinogen gamma chain.

Clone:
mCD11b

Immunogen:
Purified mouse LN CD4+ T cells

Ig Subclass:
Rat IgG2b

Purification Method:
Ion exchange column

Protein concentration:
1mg/ml in PBS (after reconstitution)

Storage Procedures:
Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.

Reconstitution:
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Stability / Shelf Life:
Two years lyophilized, one month in solution at 4oC.

Antibody Properties:
Staining and blocking antibody. For staining, use 10 µl/106 cells. This antibody will block signaling through the CD11a molecule. Titer for blocking should be determined by the investigator

Available Conjugates:
This antibody is only available conjugated to FITC.

Usage:
Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.