产品编号:ANT-134-500ug

产品描述:Mouse Anti Human CD8-biotinylated(CD8-Biotin)

反应种属:human

实验方法:

标记:Biotinylated

规格:500µg

供应商:ProSpec

价格(RMB):3500.00

订购:

说明书:

CD8 biotin Antibody
CD8, Mouse Anti-Human
Catalog No. ANT-134

Synonyms:
CD8, MAL, p32

Type:
Mouse Anti Human Monoclonal

Introduction:
CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. CD8 alpha chains binds to class-I MHC molecules alpha-3 domains.

Clone:
hCD8

Immunogen:
Purified human PBL CD8+ T cells

Ig Subclass:
Mouse IgG2a

Purification Method:
Ion exchange column

Protein concentration:
1mg/ml in PBS (after reconstitution)

Storage Procedures:
Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.

Reconstitution:
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Stability / Shelf Life:
Two years lyophilized, one month in solution at 4oC.

Antibody Properties:
Staining antibody, weakly cytotoxic. For staining, use 10 µl/106 cells. Titer for cytotoxicity should be determined by the investigator.

Available Conjugates:
This antibody is also available conjugated to FITC.

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.