产品编号:ANT-212-500ug

产品描述:Mouse Anti-Human Macrophage Inflammatory Protein-3 alpha (CCL20)(MIP-3a)

反应种属:human

实验方法:ELISA

标记:

规格:500µg

供应商:ProSpec

价格(RMB):2170.00

订购:

说明书:

MIP 3a Antibody
Macrophage Inflammatory-3 Alpha CCL20, Mouse Anti-Human
Catalog No. ANT-212

Synonyms:
C-C motif chemokine 20, Small-inducible cytokine A20, Macrophage inflammatory protein 3 alpha, MIP-3-alpha, Liver and activation-regulated chemokine, CC chemokine LARC, Beta chemokine exodus-1, CCL20, CKb4, LARC, ST38, MIP3A, MIP-3a, SCYA20.

Type:
Mouse Anti Human Monoclonal

Introduction:
Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils. CCL20 is implicated in the formation and function of mucosallymphoid tissues via chemoattraction of lymphocytesand dendritic cells towards the epithelial cellssurrounding these tissues. CCL20 elicits its effects on its target cells by binding and activating the chemokine receptor CCR6.
Gene expression of CCL20 can be induced by microbial factors such as lipopolysaccharide (LPS), and inflammatory cytokines such as tumor necrosis factorand interferon-γ, and down-regulated by IL-10. CCL20 is expressed in several tissues with highest expression observed in peripheral blood lymphocytes, lymph nodes, liver, appendix, and fetal lung and lower levels in thymus, testis, prostate and gut. The gene for CCL20 (scya20) is located on chromosome 2 in humans.

Clone:
YNR-HMIP3a.

Immunogen:
r.Human MIP-3a.

Ig Subclass:
Mouse IgG1.

Purification Method:
Protein A.

Protein concentration:
1mg/ml in PBS (after reconstitution).

Storage Procedures:
Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at ‑20oC.

Reconstitution:
Reconstitute with 0.5ml of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Stability / Shelf Life:
Two years lyophilized, one month in solution at 4oC.

Titer:
By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.