产品编号:L96498222-200

产品描述:Anti Human Coagulation Factor VIII Complex

反应种属:

实验方法:

标记:

规格:200ul

供应商:Biosense

价格(RMB):6750.00

订购:

说明书:

Anti Human Coagulation Factor VIII Complex

Background
The factor VIII complex, with a molecular weight in excess of 1 million, has 2 components: (1) factor VIII (molecular weight of 293 kDa) called factor VIII C, when measured by procoagulant activity, or factor VIII Ag, when measured immunologically; (2) factor VIII R (the von Willebrand factor or vWF) has a molecular weight of 220 kDa. Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa. Domain F5/8 type C 2 Is responsible for phospholipid binding and essential for factor VIII activity. Defects in F8 are the cause of hemophilia A (HEMA). HEMA is a common recessive X-linked coagulation disorder.

Immunogen: Purified full length native Coagulation Factor VIII-VWF-F VIII:c complex (Human)

Antigen synonyme names: AHF; Antihemophilic factor; Coagulation factor VIII; Coagulation factor VIII procoagulant component (hemophilia A); Coagulation factor VIII procoagulant component; Coagulation factor VIIIc; F8c; Factor 8C; HEMA; Procoagulant component;