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Co-planar PCBs ELISA kit 共面多氯联苯检测试剂盒

产品编号:L48200411-096

产品描述:Co-planar PCBs ELISA kit 共面多氯联苯检测试剂盒

反应种属:

实验方法:

标记:

规格:96 wells

供应商:Biosense

价格(RMB):19975.00

订购:订购

说明书:

Co-planar PCBs ELISA kit

Coplanar Polychlorinated Biphenyls (PCBs)

PCBs are industrial compounds which are known to be among the most persistent and widely distributed pollutants in the global ecosystem. They tend to bioaccumulate in the fatty tissues of animals, including humans. The non-ortho substituted congeners (coplanar) structurally resemble dioxin and exhibit the highest dioxin-like activities based on their ability to interact with the aryl hydrocarbon receptor (AhR)1. Health risk due to coplanar PCB exposure are expressed by dioxin (TEQ) equivalents, using toxicity equivalency factors (TEFs). Conventional methods for the analysis of co-PCBs use high resolution GC/MS, are expensive, time-consuming, and require specialized equipment. This ELISA had the highest sensitivity for congeners 126 and 169 (the lowest quantification limit for congener 169 is 4 pg/ml).

  • The antibody binds primarily PCB congeners with high TEF value, PCB congeners 126 and 169.
  • The assay range is between 25 ppt and 1,000 ppt (based on congener 126). This supersensitive assay allows the determination of coplanar PCBs in a wide range of environmental samples (water, soil, sediment, fish tissue, etc.).
  • Total time for measurement is less than 120 minutes.
  • The kit (96 Tests), a microtiter plate format with ready to use reagents, enables faster assay kinetics, super sensitivity, and the simultaneous measurement of multiple samples at a reasonable cost.

Samples containing PCBs within the dynamic range (25-1,000 ppt) can be directly tested in the assay after filtration.

Cross-reactivity Pattern
The cross-reactivity of the Coplanar PCB Assay for various congeners and Aroclors can be expressed as the least detectable dose (LDD) which is estimated at 90% B/Bo, or as the dose required for the 50% absorbance inhibition (50% B/Bo)

 

 

 

 

 

 

 

 

 

 

 

 

Sample Correlation
This ELISA exhibits good correlation with GC/HRMS Method 1668A.

Kit Format
Microtiter Plate Kit format, (96Tests)