产品编号:PRO-501-5ug
产品描述:Recombinant Human Ets-1(Ets-1)
反应种属:
实验方法:
标记:
规格:5ug
供应商:Prospec
价格(RMB):4050.00
说明书:
Ets-1 Human
Ets-1 Human Recombinant
Catalog No. PRO-501
Synonyms:
Protein C-ets-1, ETS-1, p54, ETS1, EWSR2, FLJ10768.
Introduction:
The proto-oncogene c-Ets-1 is a transcription factor known to regulate expression of a number of genes involved in extracellular matrix remodeling, control numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. Ets-1 interacts with the urokinase-type plasminogen activator gene enhancer and with the promoters of stromelysins-1 and collagenase-1 gene which may implicate it in this process.
The conserved ETS domain inside these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes.
Description:
Ets-1 Human Recombinant (aa 220-442) expressed in E.coli, shows a 48 kDa band on SDS-PAGE (Including GST).
The Ets-1 is purified by proprietary chromatographic techniques.
Source:
Escherichia Coli.
Physical Appearance:
Sterile Filtered clear solution.
Formulation:
Ets-1 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Stability:
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.
Applications:
• ELISA
• Inhibition Assays
• Western Blotting
Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.