产品编号:ENZ-366-10ug

产品描述:Recombinant Human PPP1R1A(PPP1R1A)

反应种属:

实验方法:

标记:

规格:10µg

供应商:Prospec

价格(RMB):1820.00

订购:

说明书:

PPP1R1A Human
Protein Phosphatase Inhibitor-1 Human Recombinant
Catalog No. ENZ-366

Synonyms:
IPP1, IPP-1, I-1, PPP1R1A, PPI-1, Protein Phosphatase Inhibitor-1, Protein phosphatase 1 regulatory subunit 1A.

Introduction:
PPP1R1A is an inhibitor of protein-phosphatase 1. IPP-1 protein plays important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP elevate IPP-1 activity. PPP1R1A activation caused cAMP to control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium, IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation.

Description:
PPP1R1A Human Recombinant fused with His tag at C-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 179 amino acids and having a molecular mass of 20 kDa.
The PPP1R1A is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered colorless solution.

Formulation:
The PPP1R1A solution contains 50mM Tris pH-8, 0.1mM PMSF, 1mM EDTA, 1mM DTT & 10% glycerol.

Stability:
PPP1R1A although stable 4°C for 4 weeks, should be stored desiccated below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Purity:
Greater than 90.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Amino acid sequence:
MEQDNSPRKI QFTVPLLEPH LDPEAAEQIR RRRPTPATLV LTSDQSSPEI DEDRIPNPHL KSTLAMSPRQ RKKMTRITPT MKELQMMVEH HLGQQQQGEE PEGAAESTGT QESRPPGIPD TEVESRLGTS GTAKKTAECI PKTHERGSKE PSTKEPSTHI PPLDSKGANS VLEHHHHHH

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.