产品编号:ENZ-361-10ug

产品描述:Recombinant Yeast Glutaredoxin 1(GRX1)

反应种属:

实验方法:

标记:

规格:10µg

供应商:Prospec

价格(RMB):800.00

订购:

说明书:

GRX1 Yeast
Glutaredoxin 1 Yeast Recombinant
Catalog No. ENZ-361

Synonyms:
Thioltransferase, GRX, GLRX1, GRX1, GRX-1, GLRX-1, Glutathione-dependent oxidoreductase 1, Glutaredoxin 1.

Introduction:
GRX1 has a glutathione-disulfide oxidoreductase activity in the presence of nadph and glutathione reductase. Reduces low molecular weight disulfides and proteins.
Glutaredoxin is a glutathione (GSH)-dependent hydrogen donor for ribonucleotide reductase and also catalyzes glutathione-disulfide oxidoreduction reactions in the presence of NADPH and glutathione reductase. GRX1 is multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage.

Description:
Glutaredoxin Saccharamyces cerevisiae Recombinant conaining 6x His tag at C-Terminus produced in E.Coli is a single, non-glycosylated, Polypeptide chain having a molecular mass of 16 kDa.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered clear colorless solution.

Formulation:
Glutaredoxin solution contains 25mM Tris-HCl pH-7.5 & 0.01% Na Azide.

Stability:
1 week at 2-10°C. For long term store at -20 to -80°C.

Purity:
Greater than 90% as determined by SDS-PAGE.

Applications:
ELISA, Western Blot, strongly binds to glutathione, reduced and oxidized.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals