产品编号:CHM-350-20ug

产品描述:Recombinant Human Platelet Factor-4 (CXCL4)(PF-4)

反应种属:

实验方法:

标记:

规格:20µg

供应商:Prospec

价格(RMB):1820.00

订购:

说明书:

PF 4 Human
Platelet Factor-4 Human Recombinant (CXCL4)
Catalog No. CHM-350

Synonyms:
CXCL4, PF-4, PF4, Iroplact, Oncostatin-A, SCYB4, MGC138298.

Introduction:
Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemocinfamily. Human PF4 is used for the proof of heparin-induced thrombocytopenia. Furthermore it is used as an inhibitor in the angiogenesis during tumor therapy.

Description:
CXCL4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 70 amino acids and having a molecular mass of 7.8 kDa.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered white lyophilized powder.

Formulation:
The protein was lyophilized without additives.

Stability:
Human CXCL4 although stable at 25°C 1 week, should be stored desiccated below -18°C.
Please prevent freeze-thaw cycles.

Purity:
Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Amino acid sequence:
The sequence of the first four N-terminal amino acids was determined and was found to be Met -Glu - Ala - Glu -Glu.

Activity Control:
Binding of HIT-antibodies.

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs,agricultural or pesticidal products, food additives or household chemicals.