产品编号:2046-1

产品描述:Alpha-2 Catenin antibody

反应种属:Human, Mouse, Rat

实验方法:WB, ICC, IP

标记:

规格:100ul

供应商:Epitomics

价格(RMB):2500.00

订购:

说明书:

Alpha-2 Catenin antibody

Cat.#: 2046-1

Rabbit Monoclonal Antibody

It has been shown that alpha N-catenin, a linker between cadherin adhesion receptors and the actin cytoskeleton, is essential for stabilizing dendritic spines in rodent hippocampal neurons in culture. Results suggest that alpha N-catenin is a key regulator for the stability of synaptic contacts (1). We show here that antibodies against alpha catenin also immunoprecipitate complexes that contain human N-cadherin, mouse P-cadherin, chicken A-CAM (adherens junction-specific CAM; also called N-cadherin) or Xenopus U-cadherin, demonstrating that alpha catenin is complexed with other cadherins (2).

Recommended Applications

WB, ICC, IP

Applications and Recommended Dilution Factors

WB: 1:1000 - 2000
ICC: 1:50
IP: 1:50

Species Reactivity

Human, Mouse, Rat

Products Data

A. Western blot analysis on mouse brain lysate using anti-alpha 2 Catenin RabMAb (cat. # 2046-1), dilution 1:2000.

  

  

Specificity

A synthetic peptide corresponding to residues in human α-2 Catenin was used as an immungen.

Storage Buffer & Conditions

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Alternative Names

CTNNA2, CAPR, Catenin alpha-2, Alpha N-catenin;Alpha-catenin-related protein

Description References

1. Abe K, et al. Nat Neurosic 7(4):357-63, 2004
2. Herrenknecht K, et al. Proc Natl Acad Sci 88(20): 9156-60, 1991