产品编号:2070-1

产品描述:Aldh7A1 antibody

反应种属:Human, Mouse

实验方法:WB, IHC. ICC, IP

标记:

规格:100ul

供应商:Epitomics

价格(RMB):2500.00

订购:

说明书:

Aldh7A1 antibody

Cat.#: 2070-1

Rabbit Monoclonal Antibody

Antiquitin (Aldh7a1) is an evolutionarily conserved protein believed to play a role in the regulation of cellular turgor. Based on sequence analysis, this protein is classified as a member of the aldehyde dehydrogenase superfamily (1). Analysis of the amount of mRNA in various rat and human tissues indicates that the largest amounts are found in rat kidney and liver and in cultured human hepatoma cells. Only minimal amounts were detected in human peripheral blood leukocytes, rat lung, or cultured human fibroblasts (2). The plant homolog of ATQ1 is thought to be involved in regulating turgor pressure, a function that also would be essential for cells of the mammalian cochlea. Northern blots of 13 human fetal tissues show antiquitin to be highly expressed in cochlea, ovary, eye, heart, and kidney (3).

Recommended Applications

WB, IHC. ICC, IP

Applications and Recommended Dilution Factors

WB: 1:5,000-20,000
IHC: 1:100-250
ICC: 1:100-250
IP: 1:30

Species Reactivity

Human, Mouse

Products Data

A.Western blot analysis on human liver lysate using anti-Aldh7a1 Rabbit Monoclonal (cat. # 2070-1).

B. Immunohistochemical analysis of paraffin-embedded human liver using anti-Aldh7a1 RabMAb (cat. #2070-1).

  

Specificity

A synthetic peptide corresponding to residues near the C-terminus of human Aldh7a1 was used as an immunogen.

Storage Buffer & Conditions

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Alternative Names

ALDH7A1, ATQ1, Alpha-aminoadipic semialdehyde dehydrogenase, Aldehyde dehydrogenase family 7 member A1;Antiquitin-1

Description References

1. Tang WK, et al. FEBS Lett 516(1-3):183-6, 2002
2. Lee P, et al. Genomics 21(2):371-8, 1994
3. Skvorak AB, et al. Genomics 46(2):191-9, 1997